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Megakaryocyte volume modulates bone marrow niche properties and cell migration dynamics

All hematopoietic cells that develop in the bone marrow must cross the endothelial barrier to enter the blood circulation. Blood platelets, however, are released by bigger protrusions of huge progenitor cells, named megakaryocytes, and enter the blood stream as so-called proplatelets before fragment...

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Dettagli Bibliografici
Pubblicato in:Haematologica
Autori principali: Gorelashvili, Maximilian G., Angay, Oğuzhan, Hemmen, Katherina, Klaus, Vanessa, Stegner, David, Heinze, Katrin G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ferrata Storti Foundation 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7109717/
https://ncbi.nlm.nih.gov/pubmed/31248970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2018.202010
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