Pregnane steroidogenesis is altered by HIV-1 Tat and morphine: Physiological allopregnanolone is protective against neurotoxic and psychomotor effects

Pregnane steroids, particularly allopregnanolone (AlloP), are neuroprotective in response to central insult. While unexplored in vivo, AlloP may confer protection against the neurological dysfunction associated with human immunodeficiency virus type 1 (HIV-1). The HIV-1 regulatory protein, trans-act...

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書誌詳細
出版年:Neurobiol Stress
主要な著者: Paris, Jason J., Liere, Philippe, Kim, Sarah, Mahdi, Fakhri, Buchanan, Meagan E., Nass, Sara R., Qrareya, Alaa N., Salahuddin, Mohammed F., Pianos, Antoine, Fernandez, Neïké, Shariat-Madar, Zia, Knapp, Pamela E., Schumacher, Michael, Hauser, Kurt F.
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2020
主題:
Articles from the Special Issue on Allopregnanolone role in the neurobiology of stress and mood disorders; Edited by Graziano Pinna
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7109513/
https://ncbi.nlm.nih.gov/pubmed/32258256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ynstr.2020.100211
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