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Combined HIV-1 Tat and Oxycodone Activate the Hypothalamic-Pituitary-Adrenal and -Gonadal Axes and Promote Psychomotor, Affective, and Cognitive Dysfunction in Female Mice

The majority of HIV(+) patients present with neuroendocrine dysfunction and ~50% experience co-morbid neurological symptoms including motor, affective, and cognitive dysfunction, collectively termed neuroHIV. In preclinical models, the neurotoxic HIV-1 regulatory protein, trans-activator of transcri...

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Detalhes bibliográficos
Publicado no:Horm Behav
Main Authors: Salahuddin, Mohammed F., Qrareya, Alaa N., Mahdi, Fakhri, Jackson, Dejun, Foster, Matthew, Vujanovic, Tamara, Box, J. Gaston, Paris, Jason J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7071558/
https://ncbi.nlm.nih.gov/pubmed/31821792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yhbeh.2019.104649
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