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A synopsis of recent developments defining how N-glycosylation impacts immunoglobulin G structure and function
Therapeutic monoclonal antibodies (mAbs) are the fastest growing group of drugs with 11 new antibodies or antibody-drug conjugates approved by the Food and Drug Administration in 2018. Many mAbs require effector function for efficacy, including antibody-dependent cell-mediated cytotoxicity triggered...
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| Udgivet i: | Glycobiology |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7109350/ https://ncbi.nlm.nih.gov/pubmed/31822882 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwz068 |
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