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A synopsis of recent developments defining how N-glycosylation impacts immunoglobulin G structure and function

Therapeutic monoclonal antibodies (mAbs) are the fastest growing group of drugs with 11 new antibodies or antibody-drug conjugates approved by the Food and Drug Administration in 2018. Many mAbs require effector function for efficacy, including antibody-dependent cell-mediated cytotoxicity triggered...

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Vydáno v:Glycobiology
Hlavní autoři: Yamaguchi, Yoshiki, Barb, Adam W
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7109350/
https://ncbi.nlm.nih.gov/pubmed/31822882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwz068
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