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Hepatocyte growth factor protects PC12 cells against OGD/R-induced injury by reducing iron

In the light of hepatocyte growth factor (HGF) the inhibiting role on the expression of hepcidin, we hypothesized that HGF might be able to reduce cell and tissue iron by increasing ferroportin 1 (Fpn1) content and Fpn1-mediated iron release from cells and tissues. The hypothesized ability of HGF to...

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Detalles Bibliográficos
Publicado en:Biosci Rep
Main Authors: Li, Siyue, Qian, Zhong-Ming, Xu, Gaojing, Zheng, Jie, Wu, Yi
Formato: Artigo
Idioma:Inglês
Publicado: Portland Press Ltd. 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7109004/
https://ncbi.nlm.nih.gov/pubmed/32186328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20200287
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