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Hepatocyte growth factor protects PC12 cells against OGD/R-induced injury by reducing iron

In the light of hepatocyte growth factor (HGF) the inhibiting role on the expression of hepcidin, we hypothesized that HGF might be able to reduce cell and tissue iron by increasing ferroportin 1 (Fpn1) content and Fpn1-mediated iron release from cells and tissues. The hypothesized ability of HGF to...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biosci Rep
Hauptverfasser: Li, Siyue, Qian, Zhong-Ming, Xu, Gaojing, Zheng, Jie, Wu, Yi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Portland Press Ltd. 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7109004/
https://ncbi.nlm.nih.gov/pubmed/32186328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20200287
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