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Hepatocyte growth factor protects PC12 cells against OGD/R-induced injury by reducing iron

In the light of hepatocyte growth factor (HGF) the inhibiting role on the expression of hepcidin, we hypothesized that HGF might be able to reduce cell and tissue iron by increasing ferroportin 1 (Fpn1) content and Fpn1-mediated iron release from cells and tissues. The hypothesized ability of HGF to...

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Bibliografske podrobnosti
izdano v:Biosci Rep
Main Authors: Li, Siyue, Qian, Zhong-Ming, Xu, Gaojing, Zheng, Jie, Wu, Yi
Format: Artigo
Jezik:Inglês
Izdano: Portland Press Ltd. 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7109004/
https://ncbi.nlm.nih.gov/pubmed/32186328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20200287
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