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Graft-versus-host disease reduces lymph node display of tissue-restricted self-antigens and promotes autoimmunity
Acute graft-versus-host disease (GVHD) is initially triggered by alloreactive T cells, which damage peripheral tissues and lymphoid organs. Subsequent transition to chronic GVHD involves the emergence of autoimmunity, although the underlying mechanisms driving this process are unclear. Here, we test...
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| Publicado no: | J Clin Invest |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7108931/ https://ncbi.nlm.nih.gov/pubmed/31917684 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI133102 |
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