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Peripheral tissues reprogram CD8(+) T cells for pathogenicity during graft-versus-host disease
Graft-versus-host disease (GVHD) is a life-threatening complication of allogeneic stem cell transplantation induced by the influx of donor-derived effector T cells (T(E)) into peripheral tissues. Current treatment strategies rely on targeting systemic T cells; however, the precise location and natur...
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| Publicat a: | JCI Insight |
|---|---|
| Autors principals: | , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Clinical Investigation
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5922296/ https://ncbi.nlm.nih.gov/pubmed/29515032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.97011 |
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