Genome-wide plasma DNA methylation features of metastatic prostate cancer

Tumor DNA circulates in the plasma of cancer patients admixed with DNA from noncancerous cells. The genomic landscape of plasma DNA has been characterized in metastatic castration-resistant prostate cancer (mCRPC) but the plasma methylome has not been extensively explored. Here, we performed next-ge...

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Vydáno v:J Clin Invest
Hlavní autoři: Wu, Anjui, Cremaschi, Paolo, Wetterskog, Daniel, Conteduca, Vincenza, Franceschini, Gian Marco, Kleftogiannis, Dimitrios, Jayaram, Anuradha, Sandhu, Shahneen, Wong, Stephen Q., Benelli, Matteo, Salvi, Samanta, Gurioli, Giorgia, Feber, Andrew, Pereira, Mariana Buongermino, Wingate, Anna Maria, Gonzalez-Billalebeitia, Enrique, De Giorgi, Ugo, Demichelis, Francesca, Lise, Stefano, Attard, Gerhardt
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2020
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7108919/
https://ncbi.nlm.nih.gov/pubmed/32149736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI130887
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