Genome-wide plasma DNA methylation features of metastatic prostate cancer

Tumor DNA circulates in the plasma of cancer patients admixed with DNA from noncancerous cells. The genomic landscape of plasma DNA has been characterized in metastatic castration-resistant prostate cancer (mCRPC) but the plasma methylome has not been extensively explored. Here, we performed next-ge...

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Veröffentlicht in:J Clin Invest
Hauptverfasser: Wu, Anjui, Cremaschi, Paolo, Wetterskog, Daniel, Conteduca, Vincenza, Franceschini, Gian Marco, Kleftogiannis, Dimitrios, Jayaram, Anuradha, Sandhu, Shahneen, Wong, Stephen Q., Benelli, Matteo, Salvi, Samanta, Gurioli, Giorgia, Feber, Andrew, Pereira, Mariana Buongermino, Wingate, Anna Maria, Gonzalez-Billalebeitia, Enrique, De Giorgi, Ugo, Demichelis, Francesca, Lise, Stefano, Attard, Gerhardt
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2020
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7108919/
https://ncbi.nlm.nih.gov/pubmed/32149736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI130887
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