Profilin 1 delivery tunes cytoskeletal dynamics toward CNS axon regeneration

After trauma, regeneration of adult CNS axons is abortive, causing devastating neurologic deficits. Despite progress in rehabilitative care, there is no effective treatment that stimulates axonal growth following injury. Using models with different regenerative capacities, followed by gain- and loss...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Pinto-Costa, Rita, Sousa, Sara C., Leite, Sérgio C., Nogueira-Rodrigues, Joana, Ferreira da Silva, Tiago, Machado, Diana, Marques, Joana, Costa, Ana Catarina, Liz, Márcia A., Bartolini, Francesca, Brites, Pedro, Costell, Mercedes, Fässler, Reinhard, Sousa, Mónica M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7108904/
https://ncbi.nlm.nih.gov/pubmed/31945017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI125771
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