Profilin 1 delivery tunes cytoskeletal dynamics toward CNS axon regeneration

After trauma, regeneration of adult CNS axons is abortive, causing devastating neurologic deficits. Despite progress in rehabilitative care, there is no effective treatment that stimulates axonal growth following injury. Using models with different regenerative capacities, followed by gain- and loss...

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Dades bibliogràfiques
Publicat a:J Clin Invest
Autors principals: Pinto-Costa, Rita, Sousa, Sara C., Leite, Sérgio C., Nogueira-Rodrigues, Joana, Ferreira da Silva, Tiago, Machado, Diana, Marques, Joana, Costa, Ana Catarina, Liz, Márcia A., Bartolini, Francesca, Brites, Pedro, Costell, Mercedes, Fässler, Reinhard, Sousa, Mónica M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7108904/
https://ncbi.nlm.nih.gov/pubmed/31945017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI125771
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