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γ-Diketone Axonopathy: Analyses of Cytoskeletal Motors and Highways in CNS Myelinated Axons

2,5-Hexanedione (HD) intoxication is associated with axon atrophy that might be responsible for the characteristic gait abnormalities, hindlimb skeletal muscle weakness and other neurological deficits that accompany neurotoxicity. Although previous mechanistic research focused on neurofilament tripl...

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Autori principali: Zhang, Lihai, Gavin, Terrence, DeCaprio, Anthony P., LoPachin, Richard M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923284/
https://ncbi.nlm.nih.gov/pubmed/20554699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfq176
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