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A Novel Immunogen Selectively Eliciting CD8(+) T Cells but Not CD4(+) T Cells Targeting Immunodeficiency Virus Antigens
Optimization of immunogen is crucial for induction of effective T-cell responses in the development of a human immunodeficiency virus (HIV) vaccine. Conventional T-cell-based vaccines have been designed to induce virus-specific CD4(+) T as well as CD8(+) T cells. However, it has been indicated that...
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| Udgivet i: | J Virol |
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| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7108830/ https://ncbi.nlm.nih.gov/pubmed/32024773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01876-19 |
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