Long-Term Control of Simian Immunodeficiency Virus Replication with Central Memory CD4(+) T-Cell Preservation after Nonsterile Protection by a Cytotoxic T-Lymphocyte-Based Vaccine

Induction of virus-specific CD8(+) cytotoxic T-lymphocyte (CTL) responses is a promising strategy for AIDS vaccine development. However, it has remained unclear if or how long-term viral containment and disease control are attainable by CTL-based nonsterile protection. Here, we present three rhesus...

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Détails bibliographiques
Auteurs principaux: Kawada, Miki, Tsukamoto, Tetsuo, Yamamoto, Hiroyuki, Takeda, Akiko, Igarashi, Hiroko, Watkins, David I., Matano, Tetsuro
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2007
Sujets:
Vaccines and Antiviral Agents
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900223/
https://ncbi.nlm.nih.gov/pubmed/17344296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02881-06
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