Mucin-Like Domain of Ebola Virus Glycoprotein Enhances Selective Oncolytic Actions against Brain Tumors

Given that the Ebola virus (EBOV) infects a wide array of organs and cells yet displays a relative lack of neurotropism, we asked whether a chimeric vesicular stomatitis virus (VSV) expressing the EBOV glycoprotein (GP) might selectively target brain tumors. The mucin-like domain (MLD) of the EBOV G...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Zhang, Xue, Zhang, Tingting, Davis, John N., Marzi, Andrea, Marchese, Anthony M., Robek, Michael D., van den Pol, Anthony N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Cellular Response to Infection
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7108827/
https://ncbi.nlm.nih.gov/pubmed/32051271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01967-19
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