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Direct inhibition of arcuate proopiomelanocortin neurons: a potential mechanism for the orexigenic actions of dynorphin

Dynorphin, an endogenous ligand of kappa (κ) opioid receptors, has multiple roles in the brain, and plays a positive role in energy balance and food intake. However, the mechanism for this is unclear. With immunocytochemistry, we find that axonal dynorphin immunoreactivity in the arcuate nucleus is...

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Detalhes bibliográficos
Main Authors: Zhang, Xiaobing, van den Pol, Anthony N
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624848/
https://ncbi.nlm.nih.gov/pubmed/23318874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.248385
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