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Kisspeptin Directly Excites Anorexigenic Proopiomelanocortin Neurons but Inhibits Orexigenic Neuropeptide Y Cells by an Indirect Synaptic Mechanism
The neuropeptide kisspeptin is necessary for reproduction, fertility, and puberty. Here, we show strong kisspeptin innervation of hypothalamic anorexigenic proopiomelanocortin (POMC) cells, coupled with a robust direct excitatory response by POMC neurons (n > 200) to kisspeptin, mediated by mecha...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2933146/ https://ncbi.nlm.nih.gov/pubmed/20668204 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2098-10.2010 |
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