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Triptolide inhibits epithelial-mesenchymal transition and induces apoptosis in gefitinib-resistant lung cancer cells

The epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI), gefitinib, is used widely to treat non-small cell lung cancer (NSCLC) with EGFR-activating mutations. Unfortunately, the acquired drug resistance promoted by epithelial-mesenchymal transition (EMT) markedly limits the clinica...

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Detalhes bibliográficos
Publicado no:Oncol Rep
Main Authors: Li, Fangqiong, Cui, Huaizhong, Jin, Xin, Gong, Xiaoting, Wang, Wei, Wang, Juan
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7107945/
https://ncbi.nlm.nih.gov/pubmed/32323848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2020.7542
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