Halofuginone inhibits radiotherapy-induced epithelial-mesenchymal transition in lung cancer

Radiotherapy is used to treat many different human tumors. Paradoxically, radiation can activate TGF-β1 signaling and induce the epithelial-mesenchymal transition (EMT), which is associated with enhanced tumor progression. This study investigated the inhibitory effects of halofuginone, a plant-deriv...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Chen, Yang, Liu, Weishuai, Wang, Peng, Hou, Hailing, Liu, Ningbo, Gong, Linlin, Wang, Youyou, Ji, Kai, Zhao, Lujun, Wang, Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342082/
https://ncbi.nlm.nih.gov/pubmed/27533085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11217
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