Hippocampal Avoidance During Whole-Brain Radiotherapy Plus Memantine for Patients With Brain Metastases: Phase III Trial NRG Oncology CC001

PURPOSE: Radiation dose to the neuroregenerative zone of the hippocampus has been found to be associated with cognitive toxicity. Hippocampal avoidance (HA) using intensity-modulated radiotherapy during whole-brain radiotherapy (WBRT) is hypothesized to preserve cognition. METHODS: This phase III tr...

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Bibliografiset tiedot
Julkaisussa:J Clin Oncol
Päätekijät: Brown, Paul D., Gondi, Vinai, Pugh, Stephanie, Tome, Wolfgang A., Wefel, Jeffrey S., Armstrong, Terri S., Bovi, Joseph A., Robinson, Cliff, Konski, Andre, Khuntia, Deepak, Grosshans, David, Benzinger, Tammie L. S., Bruner, Deborah, Gilbert, Mark R., Roberge, David, Kundapur, Vijayananda, Devisetty, Kiran, Shah, Sunjay, Usuki, Kenneth, Anderson, Bethany Marie, Stea, Baldassarre, Yoon, Harold, Li, Jing, Laack, Nadia N., Kruser, Tim J., Chmura, Steven J., Shi, Wenyin, Deshmukh, Snehal, Mehta, Minesh P., Kachnic, Lisa A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Clinical Oncology 2020
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ORIGINAL REPORTS
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7106984/
https://ncbi.nlm.nih.gov/pubmed/32058845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.19.02767
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