Hippocampal Avoidance During Whole-Brain Radiotherapy Plus Memantine for Patients With Brain Metastases: Phase III Trial NRG Oncology CC001

PURPOSE: Radiation dose to the neuroregenerative zone of the hippocampus has been found to be associated with cognitive toxicity. Hippocampal avoidance (HA) using intensity-modulated radiotherapy during whole-brain radiotherapy (WBRT) is hypothesized to preserve cognition. METHODS: This phase III tr...

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محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:J Clin Oncol
المؤلفون الرئيسيون: Brown, Paul D., Gondi, Vinai, Pugh, Stephanie, Tome, Wolfgang A., Wefel, Jeffrey S., Armstrong, Terri S., Bovi, Joseph A., Robinson, Cliff, Konski, Andre, Khuntia, Deepak, Grosshans, David, Benzinger, Tammie L. S., Bruner, Deborah, Gilbert, Mark R., Roberge, David, Kundapur, Vijayananda, Devisetty, Kiran, Shah, Sunjay, Usuki, Kenneth, Anderson, Bethany Marie, Stea, Baldassarre, Yoon, Harold, Li, Jing, Laack, Nadia N., Kruser, Tim J., Chmura, Steven J., Shi, Wenyin, Deshmukh, Snehal, Mehta, Minesh P., Kachnic, Lisa A.
التنسيق: Artigo
اللغة:Inglês
منشور في: American Society of Clinical Oncology 2020
الموضوعات:
ORIGINAL REPORTS
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC7106984/
https://ncbi.nlm.nih.gov/pubmed/32058845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.19.02767
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