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The design and development of covalent protein-protein interaction inhibitors for cancer treatment
Protein-protein interactions (PPIs) are central to a variety of biological processes, and their dysfunction is implicated in the pathogenesis of a range of human diseases, including cancer. Hence, the inhibition of PPIs has attracted significant attention in drug discovery. Covalent inhibitors have...
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| Publicado en: | J Hematol Oncol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7106679/ https://ncbi.nlm.nih.gov/pubmed/32228680 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-020-00850-0 |
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