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Emerging Screening Approaches in the Development of Nrf2–Keap1 Protein–Protein Interaction Inhibitors

Due to role of the Keap1–Nrf2 protein–protein interaction (PPI) in protecting cells from oxidative stress, the development of small molecule inhibitors that inhibit this interaction has arisen as a viable approach to combat maladies caused by oxidative stress, such as cancers, neurodegenerative dise...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Leung, Chung-Hang, Zhang, Jia-Tong, Yang, Guan-Jun, Liu, Hao, Han, Quan-Bin, Ma, Dik-Lung
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6770765/
https://ncbi.nlm.nih.gov/pubmed/31509940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20184445
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