Hypoxia drives glucose transporter 3 expression through hypoxia-inducible transcription factor (HIF)–mediated induction of the long noncoding RNA NICI

Hypoxia-inducible transcription factors (HIFs) directly dictate the expression of multiple RNA species including novel and as yet uncharacterized long noncoding transcripts with unknown function. We used pan-genomic HIF-binding and transcriptomic data to identify a novel long noncoding RNA Noncoding...

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Vydáno v:J Biol Chem
Hlavní autoři: Lauer, Victoria, Grampp, Steffen, Platt, James, Lafleur, Veronique, Lombardi, Olivia, Choudhry, Hani, Kranz, Franziska, Hartmann, Arndt, Wullich, Bernd, Yamamoto, Atsushi, Coleman, Mathew L., Ratcliffe, Peter J., Mole, David R., Schödel, Johannes
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2020
Témata:
Gene Regulation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7105321/
https://ncbi.nlm.nih.gov/pubmed/31690629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009827
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