Structural insights into TAZ2 domain–mediated CBP/p300 recruitment by transactivation domain 1 of the lymphopoietic transcription factor E2A

The E-protein transcription factors guide immune cell differentiation, with E12 and E47 (hereafter called E2A) being essential for B-cell specification and maturation. E2A and the oncogenic chimera E2A-PBX1 contain three transactivation domains (ADs), with AD1 and AD2 having redundant, independent,...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Lochhead, Marina R., Brown, Alexandra D., Kirlin, Alyssa C., Chitayat, Seth, Munro, Kim, Findlay, Jane E., Baillie, George S., LeBrun, David P., Langelaan, David N., Smith, Steven P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2020
Schlagworte:
Protein Structure and Folding
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7105314/
https://ncbi.nlm.nih.gov/pubmed/32098872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011078
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