Loss of p16 and high Ki67 labeling index is associated with poor outcome in esophageal carcinoma

The p16 tumor suppressor is coded by CDKN2A (9p21) and plays an important role during carcinogenesis and tumor progression in numerous tumor entities. The aim of our study was to evaluate the prognostic role of p16 expression and CDKN2A deletion in esophageal cancer (EC). Therefore, we analyzed p16...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Jacobsen, Frank, Kohsar, Jacob, Gebauer, Florian, Kluth, Martina, Hube-Magg, Claudia, Simon, Ronald, Bockhorn, Maximilian, Hinsch, Andrea, Burandt, Eike, Lübke, Andreas M., Steurer, Stefan, Tachezy, Michael, Sauter, Guido, Izbicki, Jacob R., Wilczak, Wildemar, Melling, Nathaniel
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2020
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7105162/
https://ncbi.nlm.nih.gov/pubmed/32256975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27507
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