Disruption of cellular proteostasis by H1N1 influenza A virus causes α-synuclein aggregation

Neurodegenerative diseases feature specific misfolded or misassembled proteins associated with neurotoxicity. The precise mechanisms by which protein aggregates first arise in the majority of sporadic cases have remained unclear. Likely, a first critical mass of misfolded proteins starts a vicious c...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Marreiros, Rita, Müller-Schiffmann, Andreas, Trossbach, Svenja V., Prikulis, Ingrid, Hänsch, Sebastian, Weidtkamp-Peters, Stefanie, Moreira, Ana Raquel, Sahu, Shriya, Soloviev, Irina, Selvarajah, Suganya, Lingappa, Vishwanath R., Korth, Carsten
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2020
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PNAS Plus
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7104400/
https://ncbi.nlm.nih.gov/pubmed/32152117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1906466117
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