Disruption of cellular proteostasis by H1N1 influenza A virus causes α-synuclein aggregation

Neurodegenerative diseases feature specific misfolded or misassembled proteins associated with neurotoxicity. The precise mechanisms by which protein aggregates first arise in the majority of sporadic cases have remained unclear. Likely, a first critical mass of misfolded proteins starts a vicious c...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Marreiros, Rita, Müller-Schiffmann, Andreas, Trossbach, Svenja V., Prikulis, Ingrid, Hänsch, Sebastian, Weidtkamp-Peters, Stefanie, Moreira, Ana Raquel, Sahu, Shriya, Soloviev, Irina, Selvarajah, Suganya, Lingappa, Vishwanath R., Korth, Carsten
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2020
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PNAS Plus
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7104400/
https://ncbi.nlm.nih.gov/pubmed/32152117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1906466117
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