Type I Interferon Receptor Signaling of Neurons and Astrocytes Regulates Microglia Activation during Viral Encephalitis

In sterile neuroinflammation, a pathological role is proposed for microglia, whereas in viral encephalitis, their function is not entirely clear. Many viruses exploit the odorant system and enter the CNS via the olfactory bulb (OB). Upon intranasal vesicular stomatitis virus instillation, we show an...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Chhatbar, Chintan, Detje, Claudia N., Grabski, Elena, Borst, Katharina, Spanier, Julia, Ghita, Luca, Elliott, David A., Jordão, Marta Joana Costa, Mueller, Nora, Sutton, James, Prajeeth, Chittappen K., Gudi, Viktoria, Klein, Michael A., Prinz, Marco, Bradke, Frank, Stangel, Martin, Kalinke, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: The Authors. 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7103936/
https://ncbi.nlm.nih.gov/pubmed/30282022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.09.003
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