Upon Intranasal Vesicular Stomatitis Virus Infection, Astrocytes in the Olfactory Bulb Are Important Interferon Beta Producers That Protect from Lethal Encephalitis

Previously we found that following intranasal (i.n.) infection with neurotropic vesicular stomatitis virus (VSV) type I interferon receptor (IFNAR) triggering of neuroectodermal cells was critically required to constrain intracerebral virus spread. To address whether locally active IFN-β was induced...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Detje, Claudia N., Lienenklaus, Stefan, Chhatbar, Chintan, Spanier, Julia, Prajeeth, Chittappen K., Soldner, Claudia, Tovey, Michael G., Schlüter, Dirk, Weiss, Siegfried, Stangel, Martin, Kalinke, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325722/
https://ncbi.nlm.nih.gov/pubmed/25540366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02044-14
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