Effects of Hypoxia and Acidosis on Cardiac Electrophysiology and Hemodynamics. Is NHE-Inhibition by Cariporide Still Advantageous?

Hypoxia often leads to severe cardiac malfunctions. It is assumed that intracellular calcium overload is -inter alia- responsible for left ventricular (LV) deterioration. Inhibition of the sodium-proton exchanger (NHE), which finally inhibits/slows calcium overload, may ameliorate cardiac function....

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Salameh, Aida, Zöbisch, Helena, Schröder, Bianca, Vigelahn, Jonas, Jahn, Mandy, Abraham, Getu, Seeger, Johannes, Dähnert, Ingo, Dhein, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7103633/
https://ncbi.nlm.nih.gov/pubmed/32265732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.00224
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