HIV-1 matrix protein repositioning in nucleocapsid region fails to confer virus-like particle assembly

The HIV-1 matrix (MA) protein is similar to nucleocapsid (NC) proteins in its propensity for self-interaction and association with RNA. Here we report on our finding that replacing MA with NC results in the production of wild type (wt)-level RNA and virus-like particles (VLPs). In contrast, construc...

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Vydáno v:Virology
Hlavní autoři: Chang, Ching-Yuan, Chang, Yu-Fen, Wang, Shiu-Mei, Tseng, Ying-Tzu, Huang, Kuo-Jung, Wang, Chin-Tien
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier Inc. 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7103396/
https://ncbi.nlm.nih.gov/pubmed/18550141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2008.05.010
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