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Severe acute respiratory syndrome coronavirus nucleocapsid protein confers ability to efficiently produce virus-like particles when substituted for the human immunodeficiency virus nucleocapsid domain

We replaced the HIV-1 nucleocapsid (NC) domain with different N-coding sequences to test SARS-CoV nucleocapsid (N) self-interaction capacity, and determined the capabilities of each chimera to direct virus-like particle (VLP) assembly. Analysis results indicate that the replacement of NC with the ca...

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Bibliografiske detaljer
Udgivet i:J Biomed Sci
Main Authors: Wang, Shui-Mei, Chang, Yu-Fen, Chen, Yi-Ming Arthur, Wang, Chin-Tien
Format: Artigo
Sprog:Inglês
Udgivet: Springer Netherlands 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7088652/
https://ncbi.nlm.nih.gov/pubmed/18592403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11373-008-9265-8
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