Incorporation of Human Immunodeficiency Virus Type 1 Reverse Transcriptase into Virus-Like Particles

We demonstrate that a genetically engineered human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) composed mainly of p66 or p51 subunits can be incorporated into virus-like particles (VLPs) when coexpressed with HIV-1 Pr55(gag). VLP-associated RT exhibited a detergent-resistant ass...

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Bibliographic Details
Main Authors: Liao, Wei-Hao, Huang, Kuo-Jung, Chang, Yu-Fen, Wang, Shiu-Mei, Tseng, Ying-Tzu, Chiang, Chien-Cheng, Wang, Jaang-Jiun, Wang, Chin-Tien
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2007
Subjects:
Genome Replication and Regulation of Viral Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900205/
https://ncbi.nlm.nih.gov/pubmed/17344306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01796-06
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