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Length of encapsidated cargo impacts stability and structure of in vitro assembled alphavirus core-like particles

In vitro assembly of alphavirus nucleocapsid cores, called core-like particles (CLPs), requires a polyanionic cargo. There are no sequence or structure requirements to encapsidate single-stranded nucleic acid cargo. In this work, we wanted to determine how the length of the cargo impacts the stabili...

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Bibliografische gegevens
Gepubliceerd in:J Phys Condens Matter
Hoofdauteurs: Rayaprolu, Vamseedhar, Moore, Alan, Wang, Joseph Che-Yen, Goh, Boon Chong, Perilla, Juan R, Zlotnick, Adam, Mukhopadhyay, Suchetana
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: IOP Publishing 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7103146/
https://ncbi.nlm.nih.gov/pubmed/28975896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/1361-648X/aa90d0
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