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Self-Assembly of an Alphavirus Core-Like Particle is Distinguished by Strong Intersubunit Association Energy and Structural Defects

Weak association energy can lead to uniform nanostructures: defects can anneal due to subunit lability. What happens when strong association energy leads to particles where defects are trapped? Alphaviruses are enveloped viruses whose icosahedral nucleocapsid core can assemble independently. We used...

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Detalles Bibliográficos
Publicado en:ACS Nano
Main Authors: Wang, Joseph Che-Yen, Chen, Chao, Rayaprolu, Vamseedhar, Mukhopadhyay, Suchetana, Zlotnick, Adam
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5683390/
https://ncbi.nlm.nih.gov/pubmed/26275088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.5b02632
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