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Decitabine: a historical review of the development of an epigenetic drug

The development of decitabine from its synthesis in 1964 to the submission of a registration file has been described. Although the unique DNA-demethylating capacity of decitabine is known for a long time, its application is under continuing investigation. The use of decitabine in MDS, AML, CML, stem...

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Publicat a:Ann Hematol
Autors principals: de Vos, Dick, van Overveld, Wendy
Format: Artigo
Idioma:Inglês
Publicat: Springer-Verlag 2005
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7103145/
https://ncbi.nlm.nih.gov/pubmed/16220311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00277-005-0008-x
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