Development of a novel cell-based assay system EPISSAY for screening epigenetic drugs and liposome formulated decitabine

BACKGROUND: Despite the potential of improving the delivery of epigenetic drugs, the subsequent assessment of changes in their epigenetic activity is largely dependent on the availability of a suitable and rapid screening bioassay. Here, we describe a cell-based assay system for screening gene react...

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Autores principales: Lim, Sue Ping, Kumar, Raman, Akkamsetty, Yamini, Wang, Wen, Ho, Kristen, Neilsen, Paul M, Walther, Diego J, Suetani, Rachel J, Prestidge, Clive, Callen, David F
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2013
Materias:
Technical Advance
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3637807/
https://ncbi.nlm.nih.gov/pubmed/23497118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-113
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