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The Development of Novel Organotin Anti-Tumor Drugs: Structure and Activity

An overview of the development of anti-tumor organotin derivatives in selected classes of compounds is presented and discussed. High to very high in vitro activity has been found, sometimes equaling that of doxorubicin. Solubility in water is an important issue, dominating the in vivo testing of com...

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Bibliografiske detaljer
Main Authors: de Vos, Dick, Willem, Rudolph, Gielen, Marcel, van Wingerden, Kyra E., Nooter, Kees
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 1998
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2365118/
https://ncbi.nlm.nih.gov/pubmed/18475842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/MBD.1998.179
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