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The Development of Novel Organotin Anti-Tumor Drugs: Structure and Activity

An overview of the development of anti-tumor organotin derivatives in selected classes of compounds is presented and discussed. High to very high in vitro activity has been found, sometimes equaling that of doxorubicin. Solubility in water is an important issue, dominating the in vivo testing of com...

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Detalhes bibliográficos
Main Authors: de Vos, Dick, Willem, Rudolph, Gielen, Marcel, van Wingerden, Kyra E., Nooter, Kees
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2365118/
https://ncbi.nlm.nih.gov/pubmed/18475842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/MBD.1998.179
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