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Bending and looping of long DNA by Polycomb repressive complex 2 revealed by AFM imaging in liquid

Polycomb repressive complex 2 (PRC2) is a histone methyltransferase that methylates histone H3 at Lysine 27. PRC2 is critical for epigenetic gene silencing, cellular differentiation and the formation of facultative heterochromatin. It can also promote or inhibit oncogenesis. Despite this importance,...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Heenan, Patrick R, Wang, Xueyin, Gooding, Anne R, Cech, Thomas R, Perkins, Thomas T
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7102998/
https://ncbi.nlm.nih.gov/pubmed/32043141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa073
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