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GO: a functional reporter system to identify and enrich base editing activity

Base editing (BE) is a powerful tool for engineering single nucleotide variants (SNVs) and has been used to create targeted mutations in cell lines, organoids and animal models. Recent development of new BE enzymes has provided an extensive toolkit for genome modification; however, identifying and i...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Katti, Alyna, Foronda, Miguel, Zimmerman, Jill, Diaz, Bianca, Zafra, Maria Paz, Goswami, Sukanya, Dow, Lukas E
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7102966/
https://ncbi.nlm.nih.gov/pubmed/32112097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa124
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