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GO: a functional reporter system to identify and enrich base editing activity
Base editing (BE) is a powerful tool for engineering single nucleotide variants (SNVs) and has been used to create targeted mutations in cell lines, organoids and animal models. Recent development of new BE enzymes has provided an extensive toolkit for genome modification; however, identifying and i...
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| Pubblicato in: | Nucleic Acids Res |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7102966/ https://ncbi.nlm.nih.gov/pubmed/32112097 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa124 |
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