Dynamic changes in cis-regulatory occupancy by Six1 and its cooperative interactions with distinct cofactors drive lineage-specific gene expression programs during progressive differentiation of the auditory sensory epithelium

The transcription factor Six1 is essential for induction of sensory cell fate and formation of auditory sensory epithelium, but how it activates gene expression programs to generate distinct cell-types remains unknown. Here, we perform genome-wide characterization of Six1 binding at different stages...

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Bibliografski detalji
Izdano u:Nucleic Acids Res
Glavni autori: Li, Jun, Zhang, Ting, Ramakrishnan, Aarthi, Fritzsch, Bernd, Xu, Jinshu, Wong, Elaine Y M, Loh, Yong-Hwee Eddie, Ding, Jianqiang, Shen, Li, Xu, Pin-Xian
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Gene regulation, Chromatin and Epigenetics
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7102962/
https://ncbi.nlm.nih.gov/pubmed/31956913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa012
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