Dynamic changes in cis-regulatory occupancy by Six1 and its cooperative interactions with distinct cofactors drive lineage-specific gene expression programs during progressive differentiation of the auditory sensory epithelium

The transcription factor Six1 is essential for induction of sensory cell fate and formation of auditory sensory epithelium, but how it activates gene expression programs to generate distinct cell-types remains unknown. Here, we perform genome-wide characterization of Six1 binding at different stages...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:Nucleic Acids Res
المؤلفون الرئيسيون: Li, Jun, Zhang, Ting, Ramakrishnan, Aarthi, Fritzsch, Bernd, Xu, Jinshu, Wong, Elaine Y M, Loh, Yong-Hwee Eddie, Ding, Jianqiang, Shen, Li, Xu, Pin-Xian
التنسيق: Artigo
اللغة:Inglês
منشور في: Oxford University Press 2020
الموضوعات:
Gene regulation, Chromatin and Epigenetics
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC7102962/
https://ncbi.nlm.nih.gov/pubmed/31956913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa012
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