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Effects of chain length and geometry on the activation of DNA damage bypass by polyubiquitylated PCNA
Ubiquitylation of the eukaryotic sliding clamp, PCNA, activates a pathway of DNA damage bypass that facilitates the replication of damaged DNA. In its monoubiquitylated form, PCNA recruits a set of damage-tolerant DNA polymerases for translesion synthesis. Alternatively, modification by K63-linked p...
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| Pubblicato in: | Nucleic Acids Res |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7102961/ https://ncbi.nlm.nih.gov/pubmed/32009145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa053 |
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