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Good guide, bad guide: spacer sequence-dependent cleavage efficiency of Cas12a
Genome editing has recently made a revolutionary development with the introduction of the CRISPR–Cas technology. The programmable CRISPR-associated Cas9 and Cas12a nucleases generate specific dsDNA breaks in the genome, after which host DNA-repair mechanisms can be manipulated to implement the desir...
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| Foilsithe in: | Nucleic Acids Res |
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| Main Authors: | , , , , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Oxford University Press
2020
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7102956/ https://ncbi.nlm.nih.gov/pubmed/31989168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz1240 |
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