Φορτώνει......
N (1)-Methylpseudouridine substitution enhances the performance of synthetic mRNA switches in cells
Synthetic messenger RNA (mRNA) tools often use pseudouridine and 5-methyl cytidine as substitutions for uridine and cytidine to avoid the immune response and cytotoxicity induced by introducing mRNA into cells. However, the influence of base modifications on the functionality of the RNA tools is poo...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Nucleic Acids Res |
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| Κύριοι συγγραφείς: | , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Oxford University Press
2020
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7102939/ https://ncbi.nlm.nih.gov/pubmed/32090264 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa070 |
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