A structural basis for restricted codon recognition mediated by 2-thiocytidine in tRNA containing a wobble position inosine

Three of six arginine codons (CGU, CGC and CGA) are decoded by two Escherichia coli tRNA(Arg) isoacceptors. The anticodon stem and loop (ASL) domains of tRNA(Arg1) and tRNA(Arg2) both contain inosine and 2-methyladenosine modifications at positions 34 (I(34)) and 37 (m(2)A(37)). tRNA(Arg1) is also m...

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Bibliographic Details
Published in:J Mol Biol
Main Authors: Vangaveti, Sweta, Cantara, William A., Spears, Jessica L., DeMirci, Hasan, Murphy, Frank V., Ranganathan, Sri V., Sarachan, Kathryn L., Agris, Paul F.
Format: Artigo
Language:Inglês
Published: 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7102896/
https://ncbi.nlm.nih.gov/pubmed/31945376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2019.12.016
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