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Mutant Huntingtin affects toll-like receptor 4 intracellular trafficking and cytokine production in mast cells
BACKGROUND: Huntington’s disease (HD) is caused by the expression of a mutated variant of Huntingtin (mHtt), which results in the complex pathology characterized by a defective function of the nervous system and altered inflammatory responses. While the neuronal effects of mHtt expression have been...
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| Gepubliceerd in: | J Neuroinflammation |
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| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
BioMed Central
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7102443/ https://ncbi.nlm.nih.gov/pubmed/32220257 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-020-01758-9 |
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