Mutant Huntingtin affects toll-like receptor 4 intracellular trafficking and cytokine production in mast cells

BACKGROUND: Huntington’s disease (HD) is caused by the expression of a mutated variant of Huntingtin (mHtt), which results in the complex pathology characterized by a defective function of the nervous system and altered inflammatory responses. While the neuronal effects of mHtt expression have been...

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Publicado en:J Neuroinflammation
Autores principales: Pérez-Rodríguez, Marian Jesabel, Ibarra-Sánchez, Alfredo, Román-Figueroa, Abraham, Pérez-Severiano, Francisca, González-Espinosa, Claudia
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7102443/
https://ncbi.nlm.nih.gov/pubmed/32220257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-020-01758-9
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