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Mapping the breast cancer metastatic cascade onto ctDNA using genetic and epigenetic clonal tracking

Circulating tumour DNA (ctDNA) allows tracking of the evolution of human cancers at high resolution, overcoming many limitations of tissue biopsies. However, exploiting ctDNA to determine how a patient’s cancer is evolving in order to aid clinical decisions remains difficult. This is because ctDNA i...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Cresswell, George D., Nichol, Daniel, Spiteri, Inmaculada, Tari, Haider, Zapata, Luis, Heide, Timon, Maley, Carlo C., Magnani, Luca, Schiavon, Gaia, Ashworth, Alan, Barry, Peter, Sottoriva, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7101390/
https://ncbi.nlm.nih.gov/pubmed/32221288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15047-9
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